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Overcoming Challenges on Your GLP-1 Journey

Last Updated: December 1, 2025
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If you’re taking a GLP-1 medication, you’re working hard to stay healthy. Even though everyone’s health journey is different, the challenges that GLP-1 medication users face can be all too common.

Digestive concerns like heartburn, gas and bloating, as well as concerns about getting the proper nutrients while eating less, are all challenges that are frequently reported by people taking GLP-1 medications.¹ However, no one should have to live with these challenges. With Haleon Huddle in your corner, you’ll have support on your journey and a selection of products to help you navigate through these challenges. You’ll also find educational resources, so you’re better equipped to ask your doctor questions—allowing you to continue on the path toward better health and wellness.

Common Hurdles for GLP-1 Medication Users

It can be difficult to deal with the challenges of starting a new medication. However, many people taking GLP-1 medications deal with similar issues—you aren’t alone! Several common challenges can be overcome with diet and lifestyle modifications. We recommend talking to your doctor about how some OTC products and supplements can help you as well.

Manage Your Digestive Challenges

A common challenge reported by people taking GLP-1 medication is heartburn. GLP-1 medications can slow down gastric emptying, meaning the stomach takes longer to move food into the intestines. This can sometimes lead to symptoms like heartburn.² You can help manage heartburn by keeping fried, acidic and spicy foods to a minimum.¹ If you still need a little help controlling heartburn—or you can’t resist indulging in some french fries on occasion—TUMS can help give you the relief you need.

TUMS is the #1 physician-recommended product for heartburn caused by the GLP-1 therapy category. TUMS Chewy Bites can provide fast and effective relief from heartburn. They’re easy to take on the go, giving you fast relief when heartburn strikes.*

GLP-1 medications use can also cause other common digestive challenges, such as pressure, bloating and fullness.³ Gas-X Ultimate Strength Softgels can help. Gas-X is the #1 physician-recommended product for bloating/gas caused by the GLP-1 therapy category. The active ingredient in Gas-X is called Simethicone, and it works by breaking down the gas bubbles in your stomach and digestive tract. By allowing your body to deal with gas when you start to experience symptoms, you have more control and freedom in your diet and lifestyle.

If heartburn, acid indigestion, sour stomach and the gas associated with those symptoms are hitting you in combination, that’s where TUMS+ GasRelief can come to your rescue. These chewable tablets offer heartburn and gas relief together in a single tablet. If you frequently experience these symptoms together, talk to your doctor to see if TUMS+ GasRelief is a good fit for you.*

Address Your Nutritional Gaps

Looking for a way to support your GLP-1 journey? Ask your doctor if Centrum Nutrient Replenish is a good fit. It is a complete multivitamin that offers 22 essential nutrients to help fill nutrient gaps and support whole body health on your GLP-1 journey, and it helps you simplify your GLP-1 routine with one easy-to-swallow mini tablet.**

A prebiotic fiber supplement, like Benefiber, is another good product to ask your doctor about. Benefiber serves as a prebiotic that helps nourish the good bacteria in your gut.** A lower-calorie diet, common when on GLP-1 medications, can make it harder to meet daily fiber recommendations.¹ Adding a fiber supplement can help bridge the gap and support digestive health.

Support Proper Hydration

It’s important to keep proper hydration in mind as we adapt our eating and drinking habits with GLP-1 use. Replenish and fortify your body, plus fuel hydration with electrolytes, to support your GLP-1 journey with the help of Emergen-C Hydration+ Electrolyte Replenishment Powder Drink Mix. It’s easy to mix with water and tastes delicious.

Also tied to hydration might be dry mouth—it can be associated with some medications, including GLP-1 therapy. If you find yourself experiencing dry mouth, ask your doctor if Biotène Dry Mouth Oral Rinse can help.

There are challenges to taking any medication, and that includes GLP-1 medications. With the power of Haleon Huddle at your back, you’ll have the resources you need to help facilitate your conversation with your healthcare provider to find the best solution to aid in your journey.

¹ https://pubmed.ncbi.nlm.nih.gov/38853526/

² https://www.mdpi.com/2077-0383/13/21/6336

³ https://doi.org/10.1007/s13679-023-00534-z

Always read the label. Use product as directed.

Consult with your healthcare provider on appropriate management of your GLP-1 medication. Please consult with your healthcare provider before taking these products, and use as directed on label.

Haleon does not sell, endorse, or promote the use of any particular GLP-1 medication.

* Ask a doctor or pharmacist before use if you are presently taking a prescription drug. Antacids may interact with certain prescription drugs.

** This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Sign Up & Save Over $70 with Haleon Huddle

Everyday health and wellness is easier with Haleon Huddle. Join now for helpful content and big time savings on products you know and love.

*Indicates required field.

I consent to the Haleon group of companies and brands (“Haleon”) collecting my Consumer Health Data. Continue reading...
I consent to the Haleon group of companies and brands (“Haleon”) sharing my Consumer Health Data with third parties Continue reading...

By signing up for Haleon newsletters, you are certifying you are 18 years of age and older.